AR and posterior cortical atrophy: Numerous studies have validated the association between the dysregulated miRNAs and the initiation of PCa toward the acquisition of metastatic phenotype, by modulating crucial processes such as androgen receptor (AR) signaling, proliferation, apoptosis, epithelial to mesenchymal transition (EMT), and metastasis [[70], [71], [72]] (refer to Fig. 2).