As shown in [Fig. 1 (E and F)], Vcam1+ MΦ cluster 7 also coexpresses CD11b (Itgam), CD11c (Itgax), Ly6C (Ly6c2), and CD64 (Fcgr1), suggesting that they may be MΦs that contribute to the formation of splenic granulomas during STm infection. The gene discussed is ITGAM; the disease is infection.