CNTNAP5 and autoimmune polyendocrinopathy: In the sex-combined MEC-APS GWAS, there was a signal on chromosome 2q14.3, located in intron 5 of CNTNAP5, with 11 genome-wide significant variants and five suggestive variants (P<10−7), associated with %VAT (Figs 1A and 2A and Table 2A).