The other mutated genes in EBV positive DLBCL were including MYC (2/9; 22.2%), TP53 (3/9; 22.2%), KMT2D (2/9; 22.2%), MYD88 (2/9; 22.2%), PIK3CA (2/9; 22.2%) NOTCH 1 (2/9; 22.2%) and TCF3 (1/9; 11.1%). The gene discussed is NOTCH1; the disease is diffuse large B-cell lymphoma.