Considering no direct evidence connecting CD38, PTPN11, NOTCH1, TLR7, and KAT2B with the pathogenesis of MMD, their roles in atherosclerosis may also provide a new perspective and direction for future research on the molecular targeted therapy of MMD (Salagianni et al., 2012; Briot et al., 2015; Xu et al., 2016; Qi et al., 2021). This evidence concerns the gene TLR7 and atherosclerosis.