Of the 68 infants with severe prolonged jaundice, three suffered from bilirubin encephalopathy, with peak bilirubin values of 469–561 μmol/L, two cases were homozygous 211G > A with G6PD mutation (c.1376 G > T and c.1388 G > A, respectively), and one was heterozygous 211G > A with G6PD deficiency (c.95 A > G). The gene discussed is G6PD; the disease is Encephalopathy.