SOX2 and urinary bladder cancer: In addition, the potassium calcium-activated channel subfamily M regulatory beta subunit 2 (KCNMB2) antisense RNA 1 (KCNMB2-AS1) was reported to enhance the stemness of bladder cancer cells by elevating the expression levels of cancer stem cell markers CD133, Nanog, Oct4, Sox2, and ALDH1 via regulation of the miR-3194–3p/smad5 signal pathway [104].