Accumulation of α-Syn has also been detected in PDGFRα+ OPCs and BCAS1+ immature oligodendroglia in the brains of MSA patients and MSA transgenic mice overexpressing human wild-type α-Syn under the control of MBP promoter (May et al., 2014; Kaji et al., 2020). The gene discussed is MBP; the disease is multiple system atrophy.