A comparison of matched tumor tissues and para-cancer tissues in the TCGA database showed that S100A11 expression was upregulated in BLCA, BRCA, CESC, CHOL, COAD, ESCA, HNSC, KIRC, KIRP, LIHC, LUAD, LUSC, READ, STAD, THCA, and UCEC, but downregulated in KICH and PRAD (Figure 2A). The gene discussed is S100A11; the disease is neoplasm.