S100A11 and neoplasm: The highest alteration frequency of S100A11 appeared in patients with LIHC with “Amplification” as the primary type, as shown in Figure 3A. In addition, S100A11 expression had a positive correlation with copy number alteration (CNA) in 22 of 33 tumor types (Figure 3B) and a negative correlation with the DNA methylation level of S100A11 in 29 of 33 tumor types (Figure 3C).