ARPC5 and neoplasm: Furthermore, LC samples harboring ARPC5 gain and amplification exhibited high mRNA expression, as shown in Fig. 6D. We also found that ARPC5 mRNA expression was significantly higher in LC tissues than in normal tissues, as shown in Fig. 6E and Fig. 6F. However, between tumor free tissues and tumor tissues, the significant difference was based on the data from TCGA database (Fig. 6E).