While only a trend towards increased presence of CD206+ cells (control [C]: 83.3 ± 16.9 cells/field versus lipedema [L] 93.20 ± 16.4 cells/field) was detected without reaching statistical significance, a significant increase of CD163+ cells in the lipedema tissue versus the control was clearly noted (P=0.010) (control [C]: 84.7± 24.6 cells/field versus lipedema [L] 106.8 ± 19.5 cells/field. This evidence concerns the gene MRC1 and Lipedema.