A third group of cancers comprised of BLCA, BRCA, UCEC, LIHC, STAD, PRAD and THCA showed a similar expression pattern with first group of cancers except for the contrast behavior of NLRP3, NLRC4, PRF1, CASP1, CASP4, and GZMA (downregulated in this group). This evidence concerns the gene CASP4 and cancer.