The KEGG analysis of DEGs showed that the pathways of Herpes simplex virus 1 infection, HIF-1 signaling pathway, NF-kappaB signaling pathway, TNF-signaling pathway, ribosome, apoptosis, legionellosis, small cell lung cancer, p53 signaling pathway, platinum drug, cellular senescence, toxoplasmosis, Epstein–Barr virus infection, human T-cell leukemia virus 1 infection, endocytosis, microRNAs in cancer, FoxO signaling pathway, valine, leucine and isoleucine degradation, rheumatoid arthritis, fluid shear stress, and atherosclerosis were the top enriched pathways (Figures 6A, S7B, C). The gene discussed is TP53; the disease is rheumatoid arthritis.