FGF23 and osteosarcoma: In this study, we examined the difference in the expression of FGF23 in osteoblasts and osteosarcoma and observed the regulation of miR-340-5p target genes by FGF23, so as to clarify the effect of FGF23 on the proliferation and migration of osteosarcoma MG-63 and U2-OS cells, providing new ideas for early diagnosis and gene therapy of osteosarcoma.