There were no significant differences between the groups with regard to educational levels, BMI, alcohol drinking, smoking status, APOE ε4 carriers, history of hypertension, diabetes and hyperlipidemia, ADL scores, the count of platelet, neutrophil, lymphocyte, and monocyte, SII and SIRI scores (all P-values > 0.05). The gene discussed is APOE; the disease is diabetes mellitus.