To further determine the role of OASL1 in virus-induced necroptotic cell death in vivo, we infected age-matched and sex-matched Oasl1+/+ and Oasl1–/– littermate mice with either MCMV-WT or MCMV-M45mutRHIM via footpad injection and monitored footpad swelling for up to 12 days post infection (d.p.i.)(Fig. 6a,b). Here, OASL is linked to infection.