BTG3 and leprosy: Indeed, immunological abnormalities are prevalent in leprosy, since systemic lupus erythematosus-like and rheumatism-like autoimmune manifestations are often observed in leprosy patients3,4, and the positive of autoantibodies like anticardiolipin antibody of IgG (ACA), anti-nuclear antibody (ANA), extractable nuclear antigen antibody (ENA), anti-Streptolysin O (ASO), anti-double stranded DNA antibody (dsDNA) and rheumatoid factor (RF) had been reported in leprosy patients5–8.