EML4 and non-small cell lung carcinoma: Three MYB-NFIB-derived peptides (QFIDSSWYL, SLASPLQPT and SLASPLQSWYL) and one NFIB-MYB-derived peptide (MMYSPICLTQT) can bind to HLA-A*02:01 to activate the immune system.78,97 The EML4-ALK fusion gene is predominantly found in young, rarely/never smoker NSCLC patients, and ~5% of NSCLC patients have this fusion mutation.