LCT and ischemic stroke: The Mendelian randomization analysis using the lactase persistence rs4988235 genotype as instrumental variable indicated that odds ratios (95% CIs) of per 100 g/day genetically predicted non-fermented milk were 1.66 (1.01, 2.72) for CHD, 1.07 (0.62, 1.85) for ischemic stroke, 1.45 (0.97, 2.16) for CVD, and 1.12 (0.77, 1.64) for CVD mortality.