PRTN3 and arthritic joint disease: Interestingly, however, we observed several monoclonal ACPA inhibiting (clones mC03 and mBVCA1) or ameliorating arthritis (mB09 and mA01; figure 1C–E), whereas other clones showed no effect in the model (mX1604, m17D08, mF1C40; figure 1 D, E), while one clone provided a slightly enhanced arthritis prevalence (mC04; figure 1D).