NTRK1 and neoplasm: SRC family kinases and receptor tyrosine kinases are involved in signaling that promotes cell survival, growth, metastasis and angiogenesis.29 30 Preclinical studies have shown that SRC family kinases are overexpressed in mucinous ovarian carcinoma tumor cells and are thought to contribute to chemotherapy resistance.30 The anti-tumor effects of dasatinib through the inhibition of SRC family kinases and several receptor tyrosine kinases such as PDGF receptors results in inhibition of cell proliferation and promotion of cell death.