ELAVL1 and cystic fibrosis: Although further investigations are needed on the impact of HuR inhibition on Pa growth, biofilm formation, and antibiotic resistance in HAEC models, our results demonstrate that targeting the HuR pathway represents an attractive therapeutic approach, especially in a context of increasing Pa resistance to antibiotics and, thus, is vital to propose alternative and complementary treatment strategies in order to improve the clinical outcomes of CF patients.