This may be reflective of opposing roles of TLR7 functions in tumor cells versus cells of the inflammatory stroma, as can also be concluded from the observation of Michaelis et al. that tumor‐attenuating effects of TLR7 agonist treatment were lost in TLR7−/− mice and instead resulted in increased growth of TLR7‐competent tumor cells in TLR7‐deficient host animals.22 Here, TLR7 is linked to neoplasm.