TLR7 and pancreatic neoplasm: The profound impact of TLR7 deficiency on the immune landscape of pancreatic tumors is also reflected by the results of our gene set enrichment analyses which revealed that a large number of GO terms related to immune system functions, such as “leukocyte activation (GO:0045321),” “lymphocyte activation (GO:0046649),” “positive regulation of innate immune response (GO:0045089),” were significantly overrepresented among the differentially regulated genes.