However, type II and type IV CaMKs were also shown in αT3-1, LbetaT2 (gonadotropes), and GH3 (somatotropes) [39], as well as in normal human pituitary and pituitary adenoma, with CaMKIV being more expressed in gonadotropin-secreting tumours and CaMKII expressed in all tumour types but poorly in growth-hormone secreting tumours. This evidence concerns the gene GH1 and neoplasm.