The PPI network and hub gene selection revealed the top three genes with the highest score degree, namely FN1, FGFR2, and SOX2. A genetic alteration study of the potential target genes revealed MMP16 and ERBB4 as the genes with the highest alterations among the breast cancer samples, with most of the alterations belonging to amplification. Here, FGFR2 is linked to breast carcinoma.