CD8A and neoplasm: The pre-treatment score from RM-wholeFC, which positively correlated with the stromal density of CD8+ TILs at the central tumor (as mentioned before; see Figure 3H), was significantly higher in patients with ypCR than in those with non-ypCR (P = 0.015, Student’s t-test; Figure 6A), which was consistent with previously reported results.