MUC5AC and cholelithiasis: Pani et al. found that a major amount of mucin in cholelithiasis and cholecystitis was sulfomucin and sialomucin, respectively. Similar to intestinal epithelium, the gallbladder also showed increased mucin secretion for stone formation and acceleration which leads to concomitant exhaustion of mucin content within the lining epithelium [14,15].