MRC1 and neoplasm: In mice, MDSCs phenotypically were defined as cells expressing markers, PMN-MDSC (CD11b+Ly6G+Ly6Clo) and M-MDSC (CD11b+Ly6G−Ly6Chi), while tumor-associated macrophages (TAMs) can be distinguished from M-MDSCs by decreased expression of Ly6C but increased expression of F4/80 and CD206 [41].