As suggested by a study enrolling 90 PCa patients whose PSA levels were > 100 ng/mL, the differences in OS or CSS were insignificant among the 3 PSA groups, namely the slightly high (100–200 ng/mL), moderately high (200–1000 ng/mL), and considerably high (> 1000 ng/mL) groups [40]. The gene discussed is KLK3; the disease is posterior cortical atrophy.