AFP and neoplasm: The rate of M-CTC positivity was significantly higher among patients with AFP ≥ 400 ng/mL (P = 0.007), tumor size ≥ 5 cm (P = 0.023), multiple tumors (P < 0.001), poorly differentiated tumors (P = 0.003), incomplete tumor capsule (P < 0.001), BCLC stage B or C (P < 0.001), MVI (P = 0.05) or PVTT (P = 0.006).