However, the role of APOL1, BNC2, EIF3L, HIST1H2BD (alias: H2BC5), HMMR, MTATP6P1, POMT1, PPP1R3E, PRPF8, RNF167, and WBP2 in IBD is unclear. The gene discussed is PPP1R3E; the disease is inflammatory bowel disease.