However, a comparative gene expression analyses of ADAR1 and APOBEC3B using multistage liver cancer datasets showed liver-cancer-specific expression of ADAR1 (Supplementary Fig. 1a, b), and a ROC analysis showed that ADAR1 expression was more specific than APOBEC3B to liver cancer (Supplementary Fig. 1c, d). Here, APOBEC3B is linked to liver cancer.