In addition, ADAR1-dependent excessive editing of canonical miR-3144-3p leads to the generation of a novel ED_miR-3144(3_A < G) mutant that specifically suppresses SLC38A4 mRNA translation to inactivate the tumor suppressor function of SLC38A4 during liver cancer progression (Fig. 7e). The gene discussed is SLC38A4; the disease is liver cancer.