Similarly, DKK2 expression per DAPI+/TREM2+/P2RY12+ microglial cell did not differ between control (0.5 ± 0.2 μm2), pathologic aging (0.7 ± 0.1 μm2), and AD groups (0.7 ± 0.4 μm2; Fig. 6A–C,E; one-way ANOVA, p = 0.7689x). Here, DKK2 is linked to Alzheimer disease.