The manuscript titled ‘Microglial expression of the Wnt signalling modulator DKK2 differs between human Alzheimer’s disease brains and mouse neurodegeneration models’ show an increase in microgliosis and microglial overexpression of Dkk2 mRNA (a homologue of Wnt-signaling antagonist- DKK1) in cortex and hippocampus of AD mouse models as well as the spinal cord of an ALS mouse model. The gene discussed is DKK2; the disease is early-onset autosomal dominant Alzheimer disease.