IL6 and neoplasm: KDM6A deficiency endowed cancer stem cell characteristics and promoted the growth of bladder cancer cells by enhancing M2 polarization through the activation of pro‐inflammatory cytokine (IL‐6) and chemokine pathways (CCL2) indirectly due to the increase in H3K27me3 and the decrease in H3K4me1.[57] Furthermore, TAMs, recruited by lncRNAs‐driven CCL2, play a vital role in tumor metastasis.