ANXA5 and hyperinsulinemic hypoglycemia, familial, 4: As shown in Fig 4A, these CIK possessed cytotoxicity properties to the MHC-deficiency, NK-sensitive K562, and MHC expression HepG2 in terms of induced cell death assessed based on the expressions of Annexin 5 and AAD7 in a dose-dependent E:T ratio manner.