Pathways with the lowest false discovery rate (FDR), not observed in the general active transcription control (H3K4me3), were related to oncogenesis (e.g., “transcriptional misregulation in cancer” and “pathways in cancer”), following the known role of KMT2A-D and particularly of KMT2C as a tumor suppressor [37]. Here, KMT2A is linked to cancer.