Thus, with the widespread use of hs-cTn, acute myocardial injury is defined as an increase or decrease in cTn values (>20%) with at least one value above the 99th percentile URL.4 Although cTn isotypes (cTnI and cTnT) are interchangeable in diagnosing AMI, they performed differently in mortality prediction.8 9 cTnT may have superiority in predicting non-cardiovascular death, while cTnI tends to be more efficient for some cardiovascular disease outcomes.10 This evidence concerns the gene TNNI3 and cardiovascular disorder.