STOML3, MROH2A, and AMY1C were differentially expressed in NPC samples as compared to normal samples with statistical significance (p < 0.01; Figure 6F–H) except for FERMT1 (Figure 6E).The sensitivity and specificity of RiskScore were calculated using the score threshold at −11.8 to identify NPC and we found that the RiskScore has 94.4% sensitivity and 100% specificity as compared with clinical diagnosis in test data set (Figure 6I). This evidence concerns the gene MROH2A and nasopharyngeal carcinoma.