In an experiment, AMPK activation and mTORC1 suppression in a state of glucose and amino acid starvation facilitate tumor proliferation by scavenging cell debris in Phosphatase and Tensin Homolog (PTEN) deficient prostate cancer cell lines and K-Ras-driven pancreatic tumors (Kim et al., 2018). Here, PTEN is linked to prostate carcinoma.