CRP and COVID-19: COVID-19 BURDEN is an acronym for CRP (> 73.1 mg/L), O2 saturation Variation (greater than 90%, 84–90%, and less than 84%), Increased PT (> 16.2 s), Diastolic blood pressure (≤ 75 mmHg), BUN (> 23 mg/dL), and Raised LDH (> 731 U/L), as shown in Table 3.