Further, IHC staining analysis of SBC3/SBC3-miR-1Zip-xenografts tumors with proliferative and angiogenesis markers (Ki67 and CD31, respectively) revealed high Ki67 and CD31 staining in SBC3-miR-1Zip tumor tissues compared to SBC3 parental (Fig. 3H). The gene discussed is MKI67; the disease is neoplasm.