KMT2C and hypopharynx cancer: In our research, GO-MF results showed that KMT2C was involved in protein binding, we found that all samples had KMT2C mutation after strict screening of the whole-exome sequencing results of ten patients, which may indicate the relationship between KMT2C and the pathogenesis of hypopharyngeal cancer, and provide thinking for future research of the pathogenesis of hypopharyngeal cancer.