Looking into the differentially expressed genes responsible for these enriched signatures, we found upregulation of important genes known to be involved in AML (Nmt1, Ifitm3, Crip1, Cd52)48–51 and downregulation of genes whose reduced expression is a common feature of acute myeloid leukemogenesis (Junb)52. Here, NMT1 is linked to acute myeloid leukemia.