Decreased expression of these two markers benefits the metastasis of tumor cells.254 On the contrary, overexpressed miR-24–3p promotes the propagation of tumor cells by interacting directly with the PER1 gene.277 Programmed death-ligand 1 (PD-L1) mRNA in salivary exosomes inhibits the damage to the inflammatory system.283. This evidence concerns the gene CD274 and neoplasm.