IgAN is the most common glomerulonephritis caused by mesangial deposition of autoantibodies of IgA.[7] Previous studies have shown the potential link between influenza vaccination with flare-up of IgA nephropathy.[8] Cases of reactivation of IgA vasculitis occurring after COVID-19 vaccination had also been reported.[9] Furthermore, Rahim et al[4] reported a recurrence of IgA nephropathy after COVID-19 vaccination in the same patient who had a similar episode 2 years earlier after receiving a recombinant zoster vaccine (Shingrix). This evidence concerns the gene CD79A and Henoch-Schoenlein purpura.