Neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, and cystatin C are the most extensively tested biomarkers for predicting CIN.[18–20] Both BNP and NT-proBNP are established heart failure biomarkers and are recommended by international guidelines.[21,22] Furthermore, brain natriuretic peptide has a prognostic value for cardiovascular morbidity and mortality in patients with CAD.[11,12] Therefore, BNP and NT-proBNP are common clinical test items used before interventional procedures. This evidence concerns the gene NPPB and cervical squamous intraepithelial neoplasia.