PTBP1, a known regulator of posttranscriptional gene expression, is involved in alternative splicing and regulation of the polyadenylation efficiency of precursor mRNA, as well as mRNA stability; also, it is closely related to the development of multiple tumors.[11–13] Previous studies have suggested that PTBP1 is highly expressed and participates in the malignant biological behavior of bladder, colon, and breast cancer cells.[14–16] However, we have not yet reviewed any pan-cancer studies that focus on the relationship between PTBP1 and various tumor types. The gene discussed is PTBP1; the disease is breast cancer.