According to The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of chronic kidney disease–mineral and bone disorder (CKD-MBD), there are some recommendations for treatment of abnormal PTH (PTH) levels in CKD-MBD. Here, PTH is linked to Marchiafava-Bignami disease.