PTK2B and pulmonary fibrosis: In a study on pulmonary fibrosis, Wang et al found that KX-01 attenuated pulmonary fibrosis by inhibiting the p-Src/p-STAT3 signaling pathway in BLM-induced pulmonary fibrosis rats.[27] Akt1, an isoform of protein kinase B, can be involved in a variety of cellular functions such as survival, metabolism, transcription and translation in the human body after being activated by various signals.