The gene encoding myotubularin-related protein 3 (MTMR3) is an autophagy-related gene that was downregulated in a genome-wide analysis of kidney biopsy samples from LN patients.[24] In the present study, we found that MTMR3 was highly expressed in subgroup I. Although subgroup I was not associated with LN, members of this subgroup were associated with the autophagy pathway. Here, MTMR3 is linked to lobular neoplasia.